The group’s overarching aim is the total synthesis of complex natural products. These natural products may originate from a variety of sources or exhibit a variety of biological activity, however what draws them to us is their structural complexity, and the greater the complexity, the better!
Through our endeavours we hope to develop original synthetic routes, confirm biosynthetic origin through biomimetic synthesis and of course synthesising meaningful quantities to enable rigorous biological studies. Over the past 20 year our group has had success in reaching these goals and examples can be seen in our publications page.
Our current research projects can be viewed, following the links below.
Total Synthesis of Mycobacterial Secondary Metabolites
Total Synthesis of Alkyl Citrate Natural Products
Total Synthesis of Thioketopiperazine Natural Products